Can You Mix Niacinamide and Hyaluronic Acid Together? How to Use It

Can You Mix Niacinamide and Hyaluronic Acid Together How to Use It

We all love to have healthy, supple and soft skin as it makes us look good and boost confidence. However, maintaining hydrated and radiant skin all the time is challenging. Several factors, such as pollution, UV rays, and hormones can affect the skin texture.

Luckily, nowadays there are many skincare products in the market that are suitable for different skin types. Whether you have dry and dull skin or oily and acne-prone, you can find products that will give fruitful results. 

Out of so many, two powerful ingredients, niacinamide and hyaluronic acid are present in most of the skincare products. If you wonder can niacinamide and hyaluronic acid should be used together, the answer is YES. 

Both these ingredients are praised for their skin benefits and combining the two can outshine their individual results. 

Let’s understand the science behind niacinamide and hyaluronic acid, their synergistic effects and ways to include them together in skincare regime. 



Niacinamide (1) is a water-soluble form of vitamin B3. It is essential for cellular digestion and DNA repair. Its wide range of benefits in skincare make it a staple in numerous formulations.

Niacinamide offers anti-inflammatory properties that make it compelling in relieving chafed skin and lightening redness. Moreover, it reduces sebum production (2), which benefits people with acne-prone skin.

It reduces pores and fine lines on the face, resulting in a smoother, more refined skin texture.

Hyaluronic Acid

Hyaluronic Acid

In skincare, hyaluronic acid (3) acts as a humectant. It can absorb atmospheric moisture into the skin and hydrate1 skin’s surface.

Using hyaluronic acid for the skin can make skin elastic and flexible and give a youthful appearance (4). It is suitable for sensitive and acne-prone skin. This makes it a versatile ingredient in skincare products.

The Synergistic Effects of Niacinamide and Hyaluronic Acid

1. Enhanced Hydration

When combined, niacinamide and hyaluronic acid synergistically boost skin hydration levels. Hyaluronic acid attracts moisture to the skin’s surface, while niacinamide helps the skin’s natural barrier. It prevents moisture loss and promotes long-term hydration.

This dual-action method creates plump, moisturized skin with increased elasticity and a radiant complexion.

2. Anti-Aging Benefits

When used together, niacinamide and hyaluronic acid offer complementary anti-aging benefits. Niacinamide decreases the growth of wrinkles and fine lines. It promotes collagen formation and increases skin elasticity.

Meanwhile, hyaluronic acid promotes deep hydration, reduces lines and wrinkles, and provides smoother results, giving more youthful-looking skin. These components work together to counteract several signs of aging, resulting in firmer skin that looks rejuvenated.

3. Skin Barrier Support

Both niacinamide and hyaluronic acid help to maintain a healthy skin barrier, albeit in different ways.

Niacinamide enhances the skin barrier by increasing ceramide formation, an essential lipid that helps the skin maintain moisture and protects it from outer aggressors. Hyaluronic acid strengthens the skin barrier by hydrating it and creating a protective barrier that shields the skin from environmental stresses.

Niacinamide and hyaluronic acid strengthen the skin’s natural defenses when used together. This results in a more durable barrier capable of enduring environmental damage and providing adequate hydration.

4. Brightening and Even Skin Tone

Niacinamide brightens the skin by inhibiting melanin formation. It minimizes the appearance of hyperpigmentation and dark patches. Hyaluronic acid, on the other hand, helps to achieve an even skin tone. It keeps the skin hydrated and encourages new cells, resulting in a smoother, more luminous complexion.

These components work together to correct uneven skin tone and dullness, resulting in brighter, more luminous skin over time.

How to Include Niacinamide and Hyaluronic Acid in Skincare for Maximum Benefits?

1. Choose Consistent Formulations

Look for skincare items containing niacinamide and hyaluronic acid in uniform formulations.

Serums, moisturizers, and substances are perfect for getting these ingredients to the skin, as they penetrate profoundly and give long-lasting hydration and nourishment.

2. Layer Strategically

To maximize the advantages of niacinamide and hyaluronic acid, layer them in your skincare routine in the proper order. Start with the item containing niacinamide, which has a smaller molecular size and can penetrate the skin more.

Follow with a hyaluronic acid-based item to bolt in moisture and upgrade hydration.

3. Patch Test

Before trying any new skincare products in your skincare regime, conduct a patch test to reduce the risk of irritation or allergic reactions. Apply a small amount of the product to an affected area and look for negative responses for 24-48 hours.


Niacinamide and hyaluronic acid are powerful combinations, delivering multiple benefits when used together. 

When these ingredients work synergistically, they can provide amazing results such as improved hydration, reduced anti-aging effects, enhanced skin barriers and skin brightening. All this helps attain a healthy, hydrated and radiant complexion. 

Understanding the advantages of niacinamide and hyaluronic acid and combining them into your skincare routine can unlock their full potential and help you achieve healthy, glowing skin.

Image Source : canva

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